Clinical Criteria: HIT

Thursday, August 07, 2008

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The point system developed by Warkentin is a useful way to estimate the likelihood of HIT based on the degree and timing of platelet drop and the presence of other symptoms based on Warkentin TE, Heparin-induced thrombocytopenia: pathogenesis and management. Br J Haematol. 2003; 121:535-555

0-2 points are awarded to each element present, for a total possible maximum score of 8

Warkentin's Point System
Thrombocytopenia	>50% fall or platelet nadir 20-100K	30-50% fall or platelet nadir 10-19K	<30% fall or platelet nadir <10K
Timing of Platelets Drop or Other Sequelae	Onset between day 5 and day 10 or <1 day if recent exposure within 100 days	Onset aftr day 10 or not clear (missing platelet counts)	Fall too early without recent heparin exposure
Thrombosis or Other Sequelae	New thrombosis; skin necrosis, acute systemic reaction following heparin bolus	Progressive or recurrent thrombosis; erythematous skin lesions; suspected thrombosis not yet proven	None
Other Causes of Thrombocytopenia	None evident	Possible other casuses	Definite other causes present
Reseults & Recommendation
Score
HIT Probability

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