| Evidence Based Critical Care |
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ICU Scores: New Simplified Acute Physiology Score (SAPS II)
JAMA 1994 May 4;271(17):1321
Le Gall JR, Lemeshow S, Saulnier F.
Faculty of Medicine Lariboisiere-Saint-Louis, Paris, France.
OBJECTIVE--To develop and validate a new Simplified Acute Physiology Score, the SAPS II, from a large sample of surgical and medical patients, and to provide a method to convert the score to a probability of hospital mortality. DESIGN AND SETTING--The SAPS II and the probability of hospital mortality were developed and validated using data from consecutive admissions to 137 adult medical and/or surgical intensive care units in 12 countries. PATIENTS--The 13,152 patients were randomly divided into developmental (65%) and validation (35%) samples. Patients younger than 18 years, burn patients, coronary care patients, and cardiac surgery patients were excluded. OUTCOME MEASURE--Vital status at hospital discharge. RESULTS--The SAPS II includes only 17 variables: 12 physiology variables, age, type of admission (scheduled surgical, unscheduled surgical, or medical), and three underlying disease variables (acquired immunodeficiency syndrome, metastatic cancer, and hematologic malignancy). Goodness-of-fit tests indicated that the model performed well in the developmental sample and validated well in an independent sample of patients (P = .883 and P = .104 in the developmental and validation samples, respectively). The area under the receiver operating characteristic curve was 0.88 in the developmental sample and 0.86 in the validation sample. CONCLUSION--The SAPS II, based on a large international sample of patients, provides an estimate of the risk of death without having to specify a primary diagnosis. This is a starting point for future evaluation of the efficiency of intensive care units
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AIDS
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HIV positive with clinical complications as pneumocystis carinii pneumonia, Kaposi's sarcoma, Lymphoma, tuberculosis or toxoplasma infection |
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lymphoma, acute leukemia, or multiple myeloma |
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proven metastasis by surgery, C.T. scan or any other method |
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